Tadalista 20 mg can be taken with or without food. It contains tadalafil, a medicine used to treat erectile dysfunction (ED). With food: You can take it before or after a meal. Food generally does not significantly affect how tadalafil works. Timing: It is usually taken at least 30 minutes before sexual activity. Its effects Tadalista 20 Mg last up to 36 hours. Alcohol: Limit alcohol, as drinking heavily can increase dizziness, low blood pressure, and other side effects. Frequency: Do not take more than one dose in 24 hours unless your doctor specifically instructs you otherwise. Important safety warning: Do not take Tadalista with nitrate medicines (such as nitroglycerin) or recreational nitrites (“poppers”), because the combination can cause a dangerous drop in blood pressure. If you take medicines for heart conditions or blood pressure, check with your doctor or pharmacist before using it.