Malegra Oral Jelly is generally intended to work relatively quickly if it contains sildenafil, the same active ingredient used in standard sildenafil ED medicines. Onset: sildenafil can begin helping with erections in about 30 minutes, with many people taking it around 1 hour before sexual activity. Sexual stimulation is still required; it does not automatically cause Malegra Oral Jelly erection. A large or high-fat meal may delay absorption, so it can take longer to work after a heavy meal. Do not take more than one sildenafil dose in 24 hours unless specifically directed by a healthcare professional. Because the exact formulation of products sold as “Malegra Oral Jelly” can vary, check the package for the active ingredient and strength. Also, sildenafil should not be combined with nitrate medicines because of the risk of a dangerous drop in blood pressure.