Filitra 20 mg (vardenafil) can be effective for men with hypertension (high blood pressure), provided their blood pressure is well controlled and a healthcare provider determines that the medication is safe for them. How it works with hypertension Vardenafil improves blood flow to the penis by relaxing blood vessels. It may still work well in men with hypertension, as high blood pressure itself is a common cause of erectile dysfunction. When it can be used safely Many people with controlled Filitra 20 mg can take Filitra 20 mg if: Their blood pressure is stable. They have been evaluated by a healthcare provider. They are not taking medications that are contraindicated. Important precautions Do not use Filitra 20 mg with nitrate medications (such as nitroglycerin or isosorbide), as this combination can cause a dangerous drop in blood pressure. If you take alpha-blockers (for high blood pressure or prostate enlargement), your healthcare provider may recommend dose adjustments or spacing the medications apart. Some other blood pressure medications may increase the chance of dizziness or lightheadedness when combined with vardenafil, although many combinations can be used safely under medical supervision.