LacNAc units can be repeated by the action of beta-1,3-N-acetylglucosaminyltransferases (such as B3GNT enzymes) to form linear poly-N-acetyllactosamine chains, also known as poly-LacNAc or the "i-antigen". These linear chains can be further modified by beta-1,6-N-acetylglucosaminyltransferases (such as GCNT2) to create branched structures, referred to as the "I-antigen".
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Jun 05, 2026
12:41 AM
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