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Message Board > How does Vilitra interact with other medications?
How does Vilitra  interact with other medications?
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kirazmattson
585 posts
Jul 03, 2025
3:29 AM
Vilitra contains Vardenafil, a PDE5 inhibitor similar to other erectile dysfunction medications like Viagra (Sildenafil) and Cialis (Tadalafil). It works by increasing blood flow to the penis to help achieve and maintain an erection in men with erectile dysfunction (ED). However, like all medications, Vilitra can interact with other drugs, which may either reduce its effectiveness or increase the risk of side effects. Here’s how Vilitra can interact with other medications: 1. Nitrates and Nitric Oxide Donors Interaction: Vilitra should never be taken with nitrate medications, such as nitroglycerin, isosorbide dinitrate, or other nitrates commonly prescribed for chest pain (angina). Risk: Combining Vilitra with nitrates can cause a severe drop in blood pressure (hypotension), which could lead to dizziness, fainting, heart attack, or stroke. The combination can be life-threatening. Example medications: Nitroglycerin Isosorbide mononitrate/dinitrate Isosorbide dinitrate Amyl nitrate (poppers) Recommendation: If you are on nitrates for chest pain or heart disease, avoid using Vilitra. 2. Alpha-Blockers Interaction: Vilitra can interact with alpha-blockers, which are commonly used to treat high blood pressure or benign prostatic hyperplasia (BPH) (enlarged prostate). Risk: Both alpha-blockers and Vilitra lower blood pressure. When taken together, this can lead to significant hypotension (low blood pressure), causing dizziness, fainting, or even a heart attack in severe cases. Example medications: Tamsulosin (Flomax) Doxazosin (Cardura) Terazosin Prazosin Recommendation: If you are using alpha-blockers, your doctor may adjust the dosage of Vilitra to ensure the combination is safe. It’s best to space out the doses of Vilitra and alpha-blockers (e.g., take Vilitra at least 4-6 hours apart from the alpha-blocker).  


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