Most therapeutic proteins undergo glycosylation, which plays a pivotal role not only in ensuring the proper folding and functionality of these proteins but also in exerting a profound impact on their pharmacokinetics, pharmacodynamics, and overall therapeutic effectiveness. To enhance the properties of therapeutic proteins, glycoengineering has emerged as a valuable method. It involves the deliberate modification of glycosylation patterns to enhance stability, solubility, and biological activity while reducing potential immunogenicity or other associated side effects.
