What is Complement System? The complement system consists of enzymatic reactions that build upon one another to regulate pathogens, inflamed cells, destroyed foreign bodies and interconnect natural and adaptive immunity. Complement pathway is triggered by 3 different routes: the classical, alternative and lectin routes. Complement activation must be carefully regulated so that unregulated inflammation and cell damage do not ensue. Studying immune disorders and researching immunotherapies depends on a robust appreciation of the complement system.
