Malegra DXT is a combination medication that contains two active ingredients: Sildenafil Citrate (100 mg) and Duloxetine (30 mg). Sildenafil Citrate is a phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED) in men, while Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI) used to treat premature ejaculation (PE).

Regarding the onset of action:

Sildenafil Citrate (Viagra Component): Sildenafil Citrate typically has a rapid onset of action, with effects starting within 30 to 60 minutes after ingestion. However, the exact onset can vary depending on individual factors such as metabolism, food intake, and overall health.

Duloxetine (Duloxetine Component): Duloxetine is primarily used to treat premature ejaculation. Its onset of action for this purpose may vary, with some individuals experiencing improvement in control over ejaculation within a few days to weeks of starting treatment.

When combined in Malegra DXT, the onset of action may vary based on how quickly each component starts working in the body. It's important to note that Malegra DXT is typically taken about 30 to 60 minutes before anticipated sexual activity, similar to how Sildenafil Citrate (Viagra) is taken for ED. This timing allows for the medication to be effective when sexual stimulation occurs.