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How does Avana 200 Mg influence the release ?
How does Avana 200 Mg influence the release ?
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kirazmattson
115 posts
Apr 16, 2024
12:00 AM
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Avana 200 mg contains avanafil as its active ingredient, and like other medications in the same class (PDE5 inhibitors), it indirectly influences the release of nitric oxide (NO) in the body.
Nitric oxide is a signaling molecule that plays a crucial role in the relaxation of smooth muscles in the blood vessels, including those in the penis. When a man is sexually stimulated, nitric oxide is released in the erectile tissue of the penis. This leads to the activation of an enzyme called guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP).
cGMP is responsible for relaxing the smooth muscles of the penile arteries and increasing blood flow to the erectile tissue, leading to an erection. However, the action of cGMP is usually short-lived because it is broken down by the enzyme phosphodiesterase type 5 (PDE5).
Here's how Avana 200 mg influences the release of nitric oxide and its effects:
Inhibition of PDE5: Avana 200 inhibits the activity of PDE5, which is responsible for breaking down cGMP in the erectile tissue. By inhibiting PDE5, avanafil helps to maintain higher levels of cGMP, which promotes prolonged relaxation of the smooth muscles in the penile arteries and increased blood flow to the penis.
Potentiation of NO Effects: By inhibiting PDE5, avanafil indirectly potentiates the effects of nitric oxide released during sexual stimulation. This allows for more sustained and effective relaxation of the smooth muscles in the penile arteries, leading to improved erectile function and the ability to achieve and maintain erections sufficient for sexual activity.
Overall, avanafil, the active ingredient in Avana 200 mg, indirectly influences the release of nitric oxide and enhances its effects, contributing to improved erectile function in men with erectile dysfunction.
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