In recent years, Gamma delta (??) T cells have become a potential avenue for adoptive immunotherapy. To date, a number of clinical trials have used ?? T cells for cancer treatment. And this type of cell has special characteristics: MHC-unrestricted cytotoxicity, secrete inflammatory cytokines, ability to distinguish transformed cells from normal cells, as well as promote the formation of antigen-specific CD81 and CD41 T cell response. Due to the important function of ?? T cell in several diseases, it is necessary to develop suitable clinical assays for ?? T cell activity and cytotoxicity. Learn more: t cell cytotoxicity