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How does Avana affect arousal?
How does Avana affect arousal?
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kirazmattson
70 posts
Mar 08, 2024
1:46 AM
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Avana, also known as Avanafil, is a medication used to treat erectile dysfunction (ED) in men. It belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. Avanafil works by increasing blood flow to the penis during sexual stimulation, which helps men achieve and maintain an erection.
Avanafil does not directly affect arousal itself. Instead, it enhances the physiological response to sexual stimulation by inhibiting the enzyme phosphodiesterase type 5 (PDE5). Here's how it works:
Nitric Oxide Release: During sexual stimulation, nitric oxide (NO) is released in the erectile tissue of the penis.
cGMP Production: Nitric oxide stimulates the production of cyclic guanosine monophosphate (cGMP), which causes the smooth muscles in the blood vessels of the penis to relax.
Increased Blood Flow: Relaxation of the smooth muscles allows blood to flow into the erectile tissue, resulting in an erection.
PDE5 Inhibition: Phosphodiesterase type 5 (PDE5) is an enzyme that breaks down cGMP, leading to a decrease in blood flow to the penis and the cessation of the erection.
Avanafil's Action: Avanafil inhibits PDE5, which prevents the breakdown of cGMP and allows it to accumulate and persist in the erectile tissue. This prolonged presence of cGMP enhances the erectile response to sexual stimulation, enabling men with ED to achieve and maintain erections.
In summary, Avana (Avanafil) works by enhancing the natural physiological process of erection in response to sexual stimulation. It does not directly affect arousal or libido; rather, it facilitates the erectile response by increasing blood flow to the penis. Therefore, sexual stimulation and arousal are still necessary for Avana to be effective in producing an erection.
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