Tadarise, containing Tadalafil as its active ingredient, is generally considered safe for long-term use when taken as prescribed and under the guidance of a healthcare professional. Tadalafil has been extensively studied and approved by regulatory authorities for the treatment of erectile dysfunction (ED). However, it's important to note that long-term use of any medication, including tadalafil Tadarise, should be done under the supervision of a healthcare professional. Regular check-ups and discussions with your doctor are crucial to ensure ongoing safety and effectiveness. While Tadarise is generally well-tolerated, it may have potential side effects. Common side effects can include headache, dizziness, flushing, nasal congestion, and indigestion. These side effects are usually mild and temporary, resolving on their own. If you experience any severe or persistent side effects, it is important to seek medical attention promptly.