While you might equate the presence of bad scents with your toilet, failing to clear any drain can allow the growth of mould and bacteria, which in turn can generate unpleasant odours in your home, according to drain cleaning services. Flush the drain with baking soda and vinegar two to three times a year. Drain the drain with hot water. Pour hot water down the drain along with 1/2 cup each of vinegar and baking soda. This combination kills bacteria, eliminates odours, and foams up to clear debris.